← Back to patent-cliff list
CAS 1638684-93-1
2-(((1R,2R,3aS,9aS)-2-hydroxy-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)ethane-1,1-diol
Codes: TREP-067
Application context (from source-drug indications)
Interstitial lung diseaseTreprostinilPulmonary hypertensionTreprostinilPulmonary arterial hypertensionTreprostinilIdiopathic pulmonary fibrosisTreprostinilPulmonary fibrosisTreprostinilIdiopathic pulmonary arterial hypertensionTreprostinil
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Treprostinil | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(1R,2R,3aS,9aS)-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalene-2,5-diol→2-bromo-1,1-dimethoxyethane→(1R,2R,3aS,9aS)-5-(2,2-dimethoxyethoxy)-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-2-ol→2-(((1R,2R,3aS,9aS)-2-hydroxy-1-((S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl)oxy)ethane-1,1-diol
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications |
|---|---|---|---|---|---|
| Qualified Partner — East China API Works | (1R,2R,3aS,9aS)-2,3,3a,4,9,9a-Hexahydro-1-[(3S)-3-hydroxyoctyl]-1H-benz[f]indene-2,5-diol Pharmaceutical Intermediates | On request | On request | On request | — |
| Unibest Nantong cGMP Site | 1-broMo-5-fluoro-2-Methyl-3-nitrobenzene Pharmaceutical Intermediates | On request | On request | On request | — |
| Unibest Taizhou GMP-like Site | methyl 4-cyclopropyl-2-fluorobenzoate Pharmaceutical Intermediates | On request | On request | On request | — |
| Qualified Partner — East China API Works | tert-butyl 2-(4-amino-6-chloropyrimidin-5-yloxy)ethylmethylcarbamate Pharmaceutical Intermediates | On request | On request | On request | — |
| Unibest Nantong cGMP Site | 2H-Benz[f]inden-2-one, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-3,3a,4,9-tetrahydro-5-methoxy-1-[(3S)-3-[(tetrahydro-2H-pyran-2-yl)oxy]octyl]-, (3aS,9R)- Pharmaceutical Intermediates | On request | On request | On request | — |
| Unibest Taizhou GMP-like Site | 2-allyl-3-methoxybenzaldehyde Pharmaceutical Intermediates | On request | On request | On request | — |
| Qualified Partner — East China API Works | (5S)-1-Decyn-5-ol Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.