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CAS 1678555-65-1
3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylic 2,2-dimethylpropanoic anhydride
Codes: (IIa)70425-2-a
Application context (from source-drug indications)
Bacterial infectionFloxacillin sodium蜂窝织炎Floxacillin sodiumChronic renal impairmentFloxacillin sodium
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Floxacillin sodium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylic acid→3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxylic 2,2-dimethylpropanoic anhydride→S-1,3-Benzothiazol-2-yl 3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbothioate→(2S,5R,6R)-6-Amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N-diethylethanamine→(+)-6-Aminopenicillanic acid→(2S,5R,6R)-6-([[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid - N,N-diethylethanamine→(2S,5R,6R)-6-([[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
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