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CAS 1704372-41-7
(R)-tert-butyl 4-((S)-(benzyloxy)((4S,5S)-2,2-dimethyl-5-(((methylsulfonyl)oxy)methyl)-1,3-dioxolan-4-yl)methyl)-2,2-dimethyloxazolidine-3-carboxylate
Codes：MIGA-037
Application context (from source-drug indications)
法布里病米加司他盐酸盐
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 米加司他盐酸盐Migalastat Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(S)-tert-butyl 2,2-dimethyl-4-(2-oxoethyl)oxazolidine-3-carboxylate→(R)-tert-butyl 4-((R,E)-4-ethoxy-1-hydroxy-4-oxobut-2-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate→(R)-tert-butyl 4-((R,E)-1-(benzyloxy)-4-ethoxy-4-oxobut-2-en-1-yl)-2,2-dimethyloxazolidine-3-carboxylate→(R)-tert-butyl 4-((1S,2R,3R)-1-(benzyloxy)-4-ethoxy-2,3-dihydroxy-4-oxobutyl)-2,2-dimethyloxazolidine-3-carboxylate→(R)-tert-butyl 4-((S)-(benzyloxy)((4S,5R)-5-(ethoxycarbonyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-2,2-dimethyloxazolidine-3-carboxylate→(R)-tert-butyl 4-((S)-(benzyloxy)((4S,5S)-5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methyl)-2,2-dimethyloxazolidine-3-carboxylate→(R)-tert-butyl 4-((S)-(benzyloxy)((4S,5S)-2,2-dimethyl-5-(((methylsulfonyl)oxy)methyl)-1,3-dioxolan-4-yl)methyl)-2,2-dimethyloxazolidine-3-carboxylate→(3S,4R,5S,6R)-5-(benzyloxy)-6-(hydroxymethyl)piperidine-3,4-diol
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