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CAS 17610-20-7
3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde
Codes: PALOV-006
Application context (from source-drug indications)
进行性肌肉骨化症PalovaroteneHepatic function declinePalovarotene异位骨化Palovarotene遗传性多发性外生骨疣PalovaroteneDry eye syndromePalovaroteneEmphysemaPalovarotene
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Palovarotene | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2,5-dimethylhexane-2,5-diol→2,5-dichloro-2,5-dimethylhexane→1-bromo-2-methylbenzene→6-bromo-1,1,4,4,7-pentamethyl-1,2,3,4-tetrahydronaphthalene→3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonitrile→3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde→methyl 4-((dimethoxyphosphoryl)methyl)benzoate→(E)-methyl 4-(2-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoate→(E)-methyl 4-(2-(3-(bromomethyl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoate→1H-pyrazole→(E)-methyl 4-(2-(3-((1H-pyrazol-1-yl)methyl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoate
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