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CAS 181375-43-9
(2alpha,5beta,7beta,10beta,13alpha)-4,10-Bis(acetyloxy)-13-([(2R,3S)-3-benzamido-3-phenyl-2-[(trimethylsilyl)oxy]propanoyl]oxy)-1-hydroxy-9-oxo-7-[(trimethylsilyl)oxy]-5,20-epoxytax-11-en-2-yl benzoat e
Codes：(V)101438-63-a
Application context (from source-drug indications)
乳腺癌Paclitaxel/Encequidar mesylate腺癌Paclitaxel/Encequidar mesylate血管肉瘤Paclitaxel/Encequidar mesylate实体瘤Paclitaxel/Encequidar mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Paclitaxel/Encequidar mesylatePaclitaxel/Encequidar mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Benzoic acid (2alpha,5beta,7beta,10beta,13alpha)-4,10-diacetoxy-1,7-dihydroxy-13-[2(R)-hydroxy-3(S)-[2-methyl-2(E)-butenoylamino]-3-phenylpropionyloxy]-9-oxo-5,20-epoxytax-11-en-2-yl ester→(2alpha,5beta,7beta,10beta,13alpha)-4,10-Bis(acetyloxy)-13-[[(2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl]oxy]-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate→(2alpha,5beta,7beta,10beta,13alpha)-4,10-Bis(acetyloxy)-13-([(2R,3S)-3-amino-3-phenyl-2-[(trimethylsilyl)oxy]propanoyl]oxy)-1-hydroxy-9-oxo-7-[(trimethylsilyl)oxy]-5,20-epoxytax-11-en-2-yl benzoate→Benzenecarboxylic acid→(2alpha,5beta,7beta,10beta,13alpha)-4,10-Bis(acetyloxy)-13-([(2R,3S)-3-benzamido-3-phenyl-2-[(trimethylsilyl)oxy]propanoyl]oxy)-1-hydroxy-9-oxo-7-[(trimethylsilyl)oxy]-5,20-epoxytax-11-en-2-yl benzoat e
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