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CAS 188923-26-4
(2R,3R)-3-(((benzyloxy)carbonyl)amino)-2-((methylsulfonyl)oxy)-4-(phenylthio)butyl 4-nitrobenzoate
Codes: NELF-023
Application context (from source-drug indications)
HIV infectionNelfinavir MesylateMyelofibrosisNelfinavir Mesylate子宫颈功能不全Nelfinavir MesylateSystemic lupus erythematosusNelfinavir MesylateNon-small cell lung cancerNelfinavir Mesylate巨细胞病毒性视网膜炎Nelfinavir Mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Nelfinavir Mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(3S,4aS,8aS)-N-(tert-butyl)decahydroisoquinoline-3-carboxamide→benzyl ((2R,3R)-4-((3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl)-3-hydroxy-1-(phenylthio)butan-2-yl)carbamate→(5R,6S)-2,2-dimethyl-6-(((R)-1-phenylethyl)amino)-1,3-dioxepan-5-ol→(S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-hydroxyethanaminium benzoate→benzyl ((S)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-hydroxyethyl)carbamate→benzyl ((R)-1-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-2-(phenylthio)ethyl)carbamate→benzyl ((2R,3R)-3,4-dihydroxy-1-(phenylthio)butan-2-yl)carbamate→(2R,3R)-3-(((benzyloxy)carbonyl)amino)-2-hydroxy-4-(phenylthio)butyl 4-nitrobenzoate→(2R,3R)-3-(((benzyloxy)carbonyl)amino)-2-((methylsulfonyl)oxy)-4-(phenylthio)butyl 4-nitrobenzoate
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