CAS 189691-06-3

Codes：Bremelanotide

Application context (from source-drug indications)

心理性性功能障碍Bremelanotide勃起功能障碍Bremelanotide肥胖症Bremelanotide肾脏疾病Bremelanotide恶心Bremelanotide生理性性功能障碍Bremelanotide

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
BremelanotideBremelanotide	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Bremelanotide原研路线steps: 9total yield: /

BREM-001→BREM-002→BREM-003→BREM-004→BREM-005→BREM-006→BREM-007→BREM-008→BREM-009→Bremelanotide

Bremelanotide优化路线steps: 9total yield: 29.47 mg

BREM-010→BREM-011→BREM-012→BREM-013→BREM-014→BREM-015→(S)-1-((4S,7S,10R,13S,16S)-4-amino-7-(4-(benzyloxy)benzyl)-10-(4-((2-chlorobenzyl)amino)butyl)-13-isobutyl-5,8,11,14-tetraoxo-1-phenyl-16-(3-(3-tosylguanidino)propyl)-2-oxa-6,9,12,15-tetraazaheptadecan-17-oyl)-N-(2-(methylamino)-2-oxoethyl)pyrrolidine-2-carboxamide→BREM-017→BREM-018→Bremelanotide

Bremelanotide优化路线steps: 9total yield: 5.0486 g

BREM-010→BREM-019→BREM-020→BREM-021→BREM-022→BREM-023→BREM-024→BREM-025→BREM-026→Bremelanotide

Bremelanotide优化路线steps: 9total yield: 6.4 g

BREM-027→BREM-028→BREM-029→BREM-030→BREM-031→BREM-032→BREM-033→BREM-034→BREM-035→Bremelanotide

Intermediates available on this site

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