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CAS 190847-56-4
(3R)-4-Bromo-3-[[tert-butyl(dimethyl)silyl]oxy]pent-4-enal
Codes：(III)101438-53-a
Application context (from source-drug indications)
乳腺癌Paclitaxel/Encequidar mesylate腺癌Paclitaxel/Encequidar mesylate血管肉瘤Paclitaxel/Encequidar mesylate实体瘤Paclitaxel/Encequidar mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Paclitaxel/Encequidar mesylatePaclitaxel/Encequidar mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(4R,5S)-3-[(3R)-4-Bromo-3-[[tert-butyl(dimethyl)silyl]oxy]pent-4-enoyl]-4-methyl-5-phenyl-1,3-oxazolidin-2-one→(3R)-4-Bromo-3-[[tert-butyl(dimethyl)silyl]oxy]pent-4-en-1-ol→(3R)-4-Bromo-3-[[tert-butyl(dimethyl)silyl]oxy]pent-4-enal→(4R,5S)-4-methyl-5-phenyl-3-propanoyl-1,3-oxazolidin-2-one→(4R,5S)-3-[(2R,3S,5R)-6-Bromo-5-[[tert-butyl(dimethyl)silyl]oxy]-3-hydroxy-2-methylhept-6-enoyl]-4-methyl-5-phenyl-1,3-oxazolidin-2-one→(2R,3S,5R)-6-Bromo-5-[[tert-butyl(dimethyl)silyl]oxy]-3-hydroxy-2-methylhept-6-enoic acid
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