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CAS 1959567-64-6
2,5-Dioxopyrrolidin-1-yl N2-(trifluoroacetyl)-L-asparaginyl-S-(triphenylmethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithinate
Codes: Atosiban-074
Application context (from source-drug indications)
产科分娩(早产)Atosiban acetate早产(孕37周前)Atosiban acetateEndometriosisAtosiban acetate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Atosiban acetate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2(S),4-Diamino-4-oxobutyric acid→N2-(Trifluoroacetyl)-L-asparagine→2,5-Dioxopyrrolidin-1-yl N2-(trifluoroacetyl)-L-asparaginate→(+)-S-Trityl-L-cysteine→2,5-Dioxopyrrolidin-1-yl N2-(trifluoroacetyl)-L-asparaginyl-S-(triphenylmethyl)-L-cysteinyl-L-prolinate→N2-(Trifluoroacetyl)-L-asparaginyl-S-(triphenylmethyl)-L-cysteine→2,5-Dioxopyrrolidin-1-yl N2-(trifluoroacetyl)-L-asparaginyl-S-(triphenylmethyl)-L-cysteinate→N2-(Trifluoroacetyl)-L-asparaginyl-S-(triphenylmethyl)-L-cysteinyl-L-proline→Nalpha-tert-Butoxycarbonyl-L-ornithine→N2-(Trifluoroacetyl)-L-asparaginyl-S-(triphenylmethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithine→2,5-Dioxopyrrolidin-1-yl N2-(trifluoroacetyl)-L-asparaginyl-S-(triphenylmethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithinate→(S)-(-)-Proline
N2-(Trifluoroacetyl)-L-asparaginyl-S-(triphenylmethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycinamide→L-Asparaginyl-S-(triphenylmethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycinamide→2,5-Dioxopyrrolidin-1-yl O-ethyl-N-[3-[(triphenylmethyl)sulfanyl]propanoyl]-D-tyrosyl-L-isoleucyl-O-tert-butyl-L-threoninate→O-Ethyl-N-[3-[(triphenylmethyl)sulfanyl]propanoyl]-D-tyrosyl-L-isoleucyl-O-tert-butyl-L-threonyl-L-asparaginyl-S-(triphenylmethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithylglycinamide→2,5-Dioxopyrrolidin-1-yl N2-(trifluoroacetyl)-L-asparaginyl-S-(triphenylmethyl)-L-cysteinyl-L-prolyl-N5-(tert-butoxycarbonyl)-L-ornithinate→Glycinamide hydrochloride
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