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CAS 19982-07-1

N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)acetamide

Codes:MEMA-003

Application context (from source-drug indications)

阿尔茨海默病盐酸美金刚/盐酸多奈哌齐

Source drugs (routes using this intermediate)

DrugTierExpiry
盐酸美金刚/盐酸多奈哌齐Memantine Hydrochloride/Donepezil HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

盐酸美金刚/盐酸多奈哌齐原研路线steps: 3total yield: 3.5 g
(1r,3r,5s,7s)-1,3-dimethyladamantane→(1r,3R,5S,7r)-1-bromo-3,5-dimethyladamantane→N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)acetamide
盐酸美金刚/盐酸多奈哌齐优化路线steps: 2total yield: 320 g
(1r,3r,5s,7s)-1,3-dimethyladamantane→N-((1r,3R,5S,7r)-3,5-dimethyladamantan-1-yl)acetamide

Intermediates available on this site

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