← Back to patent-cliff list
CAS 201856-57-7
3(R)-(1-Ethoxyethoxy)-2-oxo-4(S)-phenylazetidine-1-carboxylic acid tert-butyl ester
Codes：(Vb)140605-18-a、(III)140605-29-a
Application context (from source-drug indications)
膀胱癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)头颈癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)头颈部鳞状细胞癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)实体瘤多西他赛纳米胶束 (Samyang Biopharmaceuticals)
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 多西他赛纳米胶束 (Samyang Biopharmaceuticals)Docetaxel polymeric micelle (Samyang Biopharmaceuticals) | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
13-Acetyl-9-dihydrobaccatin-III→(2aR,4S,4aR,5R,6R,9S,11S,12S,12aR,12bS)-9,12b-Bis(acetoxy)-5,6,11-trihydroxy-4a,8,13,13-tetramethyl-4-[triethylsilyloxy]-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate→(2aR,4S,4aS,9S,11S,12S,12aR,12bS)-9,12b-Bis(acetoxy)-11-hydroxy-4a,8,13,13-tetramethyl-5,6-dioxo-4-[triethylsilyloxy]-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate→(2aR,4S,4aS,9S,11S,12S,12aR,12bS)-12b-(Acetoxy-9,11-dihydroxy-4a,8,13,13-tetramethyl-5,6-dioxo-4-[triethylsilyloxy]-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate→3(S)-[tert-Butoxycarboxamido]-2(R)-(1-ethoxyethoxy)-3-phenylpropionic acid→3(R)-(1-Ethoxyethoxy)-2-oxo-4(S)-phenylazetidine-1-carboxylic acid tert-butyl ester→(2aR,4S,4aS,9S,11S,12S,12aR,12bS)-12b-(Acetyloxy)-9-[3-[tert-butoxycarbonylamino]-2(R)-(1-ethoxyethoxy)-3(S)-phenylpropanoyloxy]-11-hydroxy-4a,8,13,13-tetramethyl-5,6-dioxo-4-[triethylsilyloxy]-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate
(2alpha,5beta,7beta,10beta,13alpha)-4-(Acetyloxy)-1,7,10,13-tetrahydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate→(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-1,13-dihydroxy-9-oxo-7,10-bis(trityloxy)-5,20-epoxytax-11-en-2-yl benzoate→3(R)-(1-Ethoxyethoxy)-2-oxo-4(S)-phenylazetidine-1-carboxylic acid tert-butyl ester→(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-13-[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-(1-ethoxyethoxy)-3-phenylpropanoyl]oxy]-1-hydroxy-9-oxo-7,10-bis(trityloxy)-5,20-epoxytax-11-en-2-yl benzoate→(2alpha,5beta,7beta,10beta,13alpha)-4-Acetoxy-13-[[(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-(1-ethoxyethoxy)-3-phenylpropanoyl]oxy]-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.