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CAS 220332-82-1
(8S,9S,10R,13S,14S,17S)-13-ethyl-17-hydroxy-11-methylene-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
Codes: ETON-018
Application context (from source-drug indications)
ContraceptionEtonogestrelAcquired immunodeficiency syndromeEtonogestrelDysmenorrhoeaEtonogestrel血崩EtonogestrelBenign prostatic hyperplasiaEtonogestrel月经失调Etonogestrel
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Etonogestrel | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(8S,9S,10R,13S,14S,17S)-13-ethyl-17-hydroxy-11-methylene-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one→(8S,9S,10R,13S,14S)-13-ethyl-11-methylene-1,6,7,8,9,10,11,12,13,14,15,16-dodecahydro-3H-cyclopenta[a]phenanthrene-3,17(2H)-dione→pyrrolidine→(8S,9S,10R,13S,14S)-13-ethyl-11-methylene-3-(pyrrolidin-1-yl)-1,2,7,8,9,10,11,12,13,14,15,16-dodecahydro-17H-cyclopenta[a]phenanthren-17-one→ethyne→(13S,14S,17S)-13-ethyl-17-hydroxy-3-methoxy-6,7,12,13,14,15,16,17-octahydro-11H-cyclopenta[a]phenanthren-11-one→(11S,13S,14S,17S)-13-ethyl-3-methoxy-11-((trimethylsilyl)methyl)-7,11,12,13,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthrene-11,17-diol→(8S,9S,11S,13S,14S,17S)-13-ethyl-3-methoxy-11-((trimethylsilyl)methyl)-4,6,7,8,9,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-11,17-diol
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