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CAS 2224-83-1
4-(4-Chlorophenyl)-1H-2,3-benzoxazin-1-one
Codes：Chlorthalidone-009
Application context (from source-drug indications)
高血压阿齐沙坦酯钾盐/氯噻酮原发性高血压阿齐沙坦酯钾盐/氯噻酮
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 阿齐沙坦酯钾盐/氯噻酮Azilsartan Medoxomil Potassium/Chlorthalidone | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-Chlorobenzene→1,2-Benzenedicarboxylic acid anhydride→2-(4-Chlorobenzoyl)benzoic acid→Sodium 2-(4-chlorobenzoyl)benzoate→4-(4-Chlorophenyl)-1H-2,3-benzoxazin-1-one→3-(4-Chlorophenyl)-2,3-dihydro-1H-isoindol-1-one→Chloridosulfuric acid→2-Chloro-5-(3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonyl chloride→2-Chloro-5-(3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzene-1-sulfonamide
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