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CAS 2227376-67-0
Di-tert-butyl (3R,4S,3'R,4'S)-3,3'-(pentane-1,5-diylbis[[di(propan-2-yl)silanediyl]oxy])bis(2-oxo-4-phenylazetidine-1-carboxylate)
Codes：(V)140605-34-a
Application context (from source-drug indications)
膀胱癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)头颈癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)头颈部鳞状细胞癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)实体瘤多西他赛纳米胶束 (Samyang Biopharmaceuticals)
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 多西他赛纳米胶束 (Samyang Biopharmaceuticals)Docetaxel polymeric micelle (Samyang Biopharmaceuticals) | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
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(3R,4S)-3-Hydroxy-1-(4-methoxyphenyl)-4-phenylazetidin-2-one→(Pentane-1,5-diyl)bis[chlorodi(propan-2-yl)silane]→(3R,4S,3'R,4'S)-3,3'-(Pentane-1,5-diylbis[[di(propan-2-yl)silanediyl]oxy])bis[1-(4-methoxyphenyl)-4-phenylazetidin-2-one]→(3R,4S,3'R,4'S)-3,3'-(Pentane-1,5-diylbis[[di(propan-2-yl)silanediyl]oxy])bis(4-phenylazetidin-2-one)→Di-tert-butyl (3R,4S,3'R,4'S)-3,3'-(pentane-1,5-diylbis[[di(propan-2-yl)silanediyl]oxy])bis(2-oxo-4-phenylazetidine-1-carboxylate)
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