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CAS 2270865-22-8
1-[2-(Methylsulfanyl)pyrimidin-4-yl]-3-phenyl-1H-pyrazole-4-carbaldehyde
Codes: (XV) 920279-3-a
Application context (from source-drug indications)
Non-small cell lung cancerLazertinib MesylateHepatic function declineLazertinib Mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Lazertinib Mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-Amino-5-fluoro-4-nitroanisole→1-Oxa-4-azacyclohexane→2-Methoxy-4-(morpholin-4-yl)-5-nitroaniline→2-Methoxy-4-morpholin-4-yl-5-nitrophenylformamide→5-Amino-2-methoxy-4-morpholin-4-ylphenylformamide→(Chloromethyl)acetyl chloride→3-Chloro-N-[5-formamido-4-methoxy-2-(morpholin-4-yl)phenyl]propanamide→N-[5-(Formylamino)-4-methoxy-2-morpholin-4-ylphenyl]acrylamide→1-[2-(Methanesulfonyl)pyrimidin-4-yl]-3-phenyl-1H-pyrazole-4-carbaldehyde→N-[5-[[4-(4-Formyl-3-phenyl-1H-pyrazol-1-yl)pyrimidin-2-yl]amino]-4-methoxy-2-(morpholin-4-yl)phenyl]prop-2-enamide→Dimethylamine hydrochloride→N-[5-[(4-[4-[(dimethylamino)methyl]-3-phenyl-1H-pyrazol-1-yl]pyrimidin-2-yl)amino]-4-methoxy-2-(morpholin-4-yl)phenyl]prop-2-enamide→3-Phenyl-1H-pyrazole-4-carbaldehyde→4-Chloro-2-(methylsulfanyl)pyrimidine→1-[2-(Methylsulfanyl)pyrimidin-4-yl]-3-phenyl-1H-pyrazole-4-carbaldehyde
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Nantong cGMP Site | 3-phenyl-1H-pyrazole-4-carbaldehyde Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | 4-Chloro-2-(methylsulfonyl)pyrimidine Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | 4-chloro-N-(2-methoxy-4-morpholino-5-nitrophenyl)pyrimidin-2-amine Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Nantong cGMP Site | 1-(2-((2-methoxy-4-morpholino-5-nitrophenyl)amino)pyrimidin-4-yl)-3-phenyl-1H-pyrazole-4-carbaldehyde Pharmaceutical Intermediates | On request | On request | On request | — | |
| Unibest Taizhou GMP-like Site | 4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)-N-(2-methoxy-4-morpholino-5-nitrophenyl)pyrimidin-2-amine Pharmaceutical Intermediates | On request | On request | On request | — | |
| Qualified Partner — East China API Works | N1-(4-(4-((dimethylamino)methyl)-3-phenyl-1H-pyrazol-1-yl)pyrimidin-2-yl)-6-methoxy-4-morpholinobenzene-1,3-diamine Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.