← Back to patent-cliff list
CAS 2304609-25-2
(2R,6S)-2,6-dimethylpiperazine
Codes: AILDE-003, ENSAR-012
Application context (from source-drug indications)
Erectile dysfunctionAildenafil CitrateNon-small cell lung cancerEnsartinib HydrochlorideLung cancerEnsartinib HydrochlorideBrain metastasesEnsartinib HydrochlorideNon-Hodgkin lymphomaEnsartinib HydrochlorideHepatoblastomaEnsartinib HydrochlorideOsteosarcomaEnsartinib Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Aildenafil Citrate | Tier C — Watch / trade | - |
| Ensartinib Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-ethoxybenzoic acid→5-(chlorosulfonyl)-2-ethoxybenzoyl chloride→(2R,6S)-2,6-dimethylpiperazine→5-(((3R,5S)-3,5-dimethylpiperazin-1-yl)sulfonyl)-2-ethoxybenzoic acid→5-(((3R,5S)-3,5-dimethylpiperazin-1-yl)sulfonyl)-2-ethoxybenzoyl chloride hydrochloride→4-amino-1-methyl-3-propyl-1H-pyrazole-5-carboxamide→4-(5-(((3R,5S)-3,5-dimethylpiperazin-1-yl)sulfonyl)-2-ethoxybenzamido)-1-methyl-3-propyl-1H-pyrazole-5-carboxamide→5-(5-(((3R,5S)-3,5-dimethylpiperazin-1-yl)sulfonyl)-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one→5-(5-(((3R,5S)-3,5-dimethylpiperazin-1-yl)sulfonyl)-2-ethoxyphenyl)-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one 2-hydroxypropane-1,2,3-tricarboxylate
3,6-dichloropyridazine→6-chloropyridazin-3-amine→4-bromo-6-chloropyridazin-3-amine→1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol→(R)-6-chloro-4-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridazin-3-amine→ENSAR-006→ENSAR-007→ENSAR-008→methyl 4-aminobenzoate→ENSAR-010→ENSAR-011→(2R,6S)-2,6-dimethylpiperazine→ENSAR-013→1-(2,6-dichloro-3-fluorophenyl)ethan-1-ol
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.