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CAS 2362015-36-7

(2-Amino-3-ethylphenyl)(4-bromophenyl)methanone

Codes: Bromfenac Sodium-030

Application context (from source-drug indications)

Inflammatory diseaseBromfenac SodiumPostoperative painBromfenac Sodium眼睛发炎Bromfenac Sodium眼睛疼痛Bromfenac SodiumDry eye syndromeBromfenac Sodium黄斑水肿Bromfenac Sodium

Source drugs (routes using this intermediate)

DrugTierExpiry
Bromfenac SodiumTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Bromfenac SodiumOptimised routesteps: 4total yield: 83.27g(Bromfenac Sodium (API))
1-Ethyl-2-nitrobenzene→2-Ethylaniline→4-Bromobenzoyl chloride→(2-Amino-3-ethylphenyl)(4-bromophenyl)methanone→N,N-Dimethylformamide dimethyl acetal→[2-Amino-3-[3-(dimethylamino)prop-2-en-1-yl]phenyl](4-bromophenyl)methanone

Intermediates available on this site

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