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CAS 26054-60-4
(S)-benzyl (2-oxooxetan-3-yl)carbamate
Codes: NELF-001
Application context (from source-drug indications)
HIV infectionNelfinavir MesylateMyelofibrosisNelfinavir Mesylate子宫颈功能不全Nelfinavir MesylateSystemic lupus erythematosusNelfinavir MesylateNon-small cell lung cancerNelfinavir Mesylate巨细胞病毒性视网膜炎Nelfinavir Mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Nelfinavir Mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
benzyl ((R)-1-((S)-oxiran-2-yl)-2-(phenylthio)ethyl)carbamate→(3S,4aS,8aS)-N-(tert-butyl)decahydroisoquinoline-3-carboxamide→benzyl ((2R,3R)-4-((3S,4aS,8aS)-3-(tert-butylcarbamoyl)octahydroisoquinolin-2(1H)-yl)-3-hydroxy-1-(phenylthio)butan-2-yl)carbamate→(3S,4aS,8aS)-2-((2R,3R)-3-amino-2-hydroxy-4-(phenylthio)butyl)-N-(tert-butyl)decahydroisoquinoline-3-carboxamide→3-hydroxy-2-methylbenzoic acid→aniline→3-methoxybenzoyl chloride→3-methoxy-N-phenylbenzamide→3-methoxy-2-methyl-N-phenylbenzamide→(S)-benzyl (2-oxooxetan-3-yl)carbamate→benzenethiol→(R)-2-(((benzyloxy)carbonyl)amino)-3-(phenylthio)propanoic acid→3-methyl-1-nitro-1-nitrosoguanidine→(S)-(2-(((benzyloxy)carbonyl)amino)-3-oxo-2-((phenylthio)methyl)azetidin-1-ium-1-ylidene)amide→(R)-benzyl (4-chloro-3-oxo-1-(phenylthio)butan-2-yl)carbamate→benzyl ((2R,3S)-4-chloro-3-hydroxy-1-(phenylthio)butan-2-yl)carbamate
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