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CAS 2738483-63-9
(2S,3aS,6aS)-1-[(2S)-2-[(tert-Butoxycarbonyl)[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
Codes:Ramipril-080
Application context (from source-drug indications)
高胆固醇血症阿托伐他汀钙/雷米普利高血压阿托伐他汀钙/雷米普利
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 阿托伐他汀钙/雷米普利Atorvastatin Calcium Hydrate/Ramipril | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
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N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine→N-(tert-Butoxycarbonyl)-N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanine→(2S,3aS,6aS)-Octahydrocyclopenta[b]pyrrole-2-carboxylic acid hydrochloride→(2S,3aS,6aS)-1-[(2S)-2-[(tert-Butoxycarbonyl)[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
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