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CAS 2738483-63-9

(2S,3aS,6aS)-1-[(2S)-2-[(tert-Butoxycarbonyl)[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid

Codes:Ramipril-080

Application context (from source-drug indications)

高胆固醇血症阿托伐他汀钙/雷米普利高血压阿托伐他汀钙/雷米普利

Source drugs (routes using this intermediate)

DrugTierExpiry
阿托伐他汀钙/雷米普利Atorvastatin Calcium Hydrate/RamiprilTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

阿托伐他汀钙/雷米普利工艺路线steps: 3total yield: 723.11g(Ramipril (Free))
N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine→N-(tert-Butoxycarbonyl)-N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanine→(2S,3aS,6aS)-Octahydrocyclopenta[b]pyrrole-2-carboxylic acid hydrochloride→(2S,3aS,6aS)-1-[(2S)-2-[(tert-Butoxycarbonyl)[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid

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