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CAS 2765664-73-9
tert-Butyl (2S)-2-(4-[4-[(1S,4R)-8-hydroxy-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]phenyl]-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
Codes: Emitasvir Phosphate-026
Application context (from source-drug indications)
Hepatitis CEmitasvir PhosphateRenal impairmentEmitasvir PhosphateHepatic function declineEmitasvir PhosphateChronic hepatitis CEmitasvir Phosphate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Emitasvir Phosphate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
tert-Butyl (2S)-2-[4-(4-[(1S,4R)-8-[(trifluoromethanesulfonyl)oxy]-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]phenyl)-1H-imidazol-2-yl]pyrrolidine-1-carboxylate→tert-Butyl (2S)-2-[4-[4-(3,3,4,4-tetramethylborolan-1-yl)phenyl]-1H-imidazol-2-yl]pyrrolidine-1-carboxylate→1,2,3,4-Tetrahydro-1,4-methanonaphthalene-5,8-diol→1,2,3,4-Tetrahydro-1,4-methanonaphthalene-5,8-diyl diacetate→(1R,4S)-8-Hydroxy-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl acetate→(1R,4S)-8-[(Trifluoromethanesulfonyl)oxy]-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl acetate→tert-Butyl (2S)-2-(4-[4-[(1S,4R)-8-hydroxy-1,2,3,4-tetrahydro-1,4-methanonaphthalen-5-yl]phenyl]-1H-imidazol-2-yl)pyrrolidine-1-carboxylate
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