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CAS 28659-87-2
(S)-2-bromo-4-methylpentanoic acid
Codes: PREG-025
Application context (from source-drug indications)
FibromyalgiaPregabalinSeizurePregabalinPostherpetic neuralgiaPregabalin神经痛PregabalinPartial-onset seizurePregabalinDiabetic neuropathyPregabalin
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Pregabalin | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(S)-2-amino-4-methylpentanoic acid→(S)-2-bromo-4-methylpentanoic acid→tert-butyl (S)-2-bromo-4-methylpentanoate→2-(tert-butyl) 1,1-diethyl (S)-4-methylpentane-1,1,2-tricarboxylate→(S)-2-(1,3-diethoxy-1,3-dioxopropan-2-yl)-4-methylpentanoic acid→(S)-4-isobutyldihydrofuran-2(3H)-one→ethyl (S)-3-(iodomethyl)-5-methylhexanoate→ethyl (S)-3-(azidomethyl)-5-methylhexanoate→(S)-3-(azidomethyl)-5-methylhexanoic acid
Intermediates available on this site
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