← Back to patent-cliff list
CAS 289703-22-6
Benzoic acid (3R,7R,12R)-4(S)-(acetyloxy)-1(S),15(S)-dihydroxy-10(S),14,17,17-tetramethyl-11-oxo-9(S),12(R)-bis[(2(S)2,2,2-trichloroacetyl)oxy]-6-oxatetracyclo[11.3.1.0(3,10).0(4,7)]heptadec-13-en-2-yl ester
Codes：(II)140605-26-a
Application context (from source-drug indications)
膀胱癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)头颈癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)头颈部鳞状细胞癌多西他赛纳米胶束 (Samyang Biopharmaceuticals)实体瘤多西他赛纳米胶束 (Samyang Biopharmaceuticals)
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 多西他赛纳米胶束 (Samyang Biopharmaceuticals)Docetaxel polymeric micelle (Samyang Biopharmaceuticals) | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(2alpha,5beta,7beta,10beta,13alpha)-4-(Acetyloxy)-1,7,10,13-tetrahydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate→Benzoic acid (3R,7R,12R)-4(S)-(acetyloxy)-1(S),15(S)-dihydroxy-10(S),14,17,17-tetramethyl-11-oxo-9(S),12(R)-bis[(2(S)2,2,2-trichloroacetyl)oxy]-6-oxatetracyclo[11.3.1.0(3,10).0(4,7)]heptadec-13-en-2-yl ester→(4S,5R)-4-Phenyl-2-(tribromomethyl)-1,3-oxazolidine-5-carboxylic acid→(2alpha,5beta,7beta,10beta,13alpha)-4-(Acetyloxy)-1-hydroxy-9-oxo-2-[(phenylcarbonyl)oxy]-7,10-bis[(trichloroacetyl)oxy]-5,20-epoxytax-11-en-13-yl (4S,5R)-4-phenyl-2-(tribromomethyl)-1,3-oxazolidine-5-carboxylate→(2alpha,5beta,7beta,10beta,13alpha)-4-(Acetyloxy)-13-[[(2R,3S)-3-amino-2-hydroxy-3-phenylpropanoyl]oxy]-1-hydroxy-9-oxo-7,10-bis[(trichloroacetyl)oxy]-5,20-epoxytax-11-en-2-yl benzoate→Bis(1,1-dimethylethyl) dicarbonoate→(2alpha,5beta,7beta,10beta,13alpha)-4-(Acetyloxy)-13-([(2R,3S)-3-[(tert-butoxycarbonyl)amino]-2-hydroxy-3-phenylpropanoyl]oxy)-1-hydroxy-9-oxo-7,10-bis[(trichloroacetyl)oxy]-5,20-epoxytax-11-en-2-yl benzoate→(2R,3S)-3-Phenylisoserine methyl ester→Tribromoacetaldehyde→Methyl (4S,5R)-4-phenyl-2-(tribromomethyl)-1,3-oxazolidine-5-carboxylate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.