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CAS 29358-99-4
ethyl (2S)-2-acetamido-3-(4-hydroxy-3,5-dinitrophenyl)propanoate
Codes: Levothyroxine Sodium-008
Application context (from source-drug indications)
ComaLevothyroxine Sodium粘液性水肿昏迷Levothyroxine SodiumHypothyroidismLevothyroxine SodiumThyroid cancerLevothyroxine SodiumHyperthyroidismLevothyroxine SodiumObesityLevothyroxine Sodium
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Levothyroxine Sodium | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(-)-alpha-Amino-p-hydroxyhydrocinnamic acid→(2S)-2-amino-3-(4-hydroxy-3,5-dinitrophenyl)propanoic acid→(2S)-2-acetamido-3-(4-hydroxy-3,5-dinitrophenyl)propanoic acid→ethyl (2S)-2-acetamido-3-(4-hydroxy-3,5-dinitrophenyl)propanoate→ethyl (2S)-2-acetamido-3-(4-{[(4-methylbenzene)sulfonyl]oxy}-3,5-dinitrophenyl)propanoate→4-Hydroxyanisole→ethyl (2S)-2-acetamido-3-[4-(4-methoxyphenoxy)-3,5-dinitrophenyl]propanoate→ethyl (2S)-3-[3,5-diamino-4-(4-methoxyphenoxy)phenyl]-2-acetamidopropanoate→(2S)-3-[3,5-diiodo-4-(4-methoxyphenoxy)phenyl]-2-acetamidopropanoic acid→3,5-Diiodo-4-(4-hydroxyphenoxy)-L-phenylalanine
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