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CAS 3083-77-0

1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Codes: (I)70439-1-a, (III)229059-10-a

Application context (from source-drug indications)

巨细胞病毒感染Vidarabine MonophosphateHerpesvirus infectionVidarabine Monophosphate

Source drugs (routes using this intermediate)

DrugTierExpiry
Vidarabine MonophosphateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Vidarabine MonophosphateOptimised routesteps: 2total yield: /
1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione→(1xi)-1,4-Anhydro-1-phosphono-D-arabinitol→6-Aminopurine
Vidarabine MonophosphateOptimised routesteps: 1total yield: /
1,2,3,4-Tetrahydropyrimidine-2,4-dione→[(2R,3S,4S,5R)-3,4,5,6-Tetrahydroxyoxan-2-yl]methyl phosphate→1-((2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

Intermediates available on this site

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