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CAS 350583-44-7
methyl (2R,3S)-3-amino-3-phenyl-2-[(triethylsilyl)oxy]propanoate
Codes：(XI)101438-34-a
Application context (from source-drug indications)
乳腺癌Paclitaxel/Encequidar mesylate腺癌Paclitaxel/Encequidar mesylate血管肉瘤Paclitaxel/Encequidar mesylate实体瘤Paclitaxel/Encequidar mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Paclitaxel/Encequidar mesylatePaclitaxel/Encequidar mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(+)-Diethyl L-tartrate→(2S,3S)-3-(benzyloxy)butane-1,2,4-triol→(2S)-2-(benzyloxy)-3-hydroxypropanal→1-Phenylmethylamine→methyl (2R,3S)-3-(benzylamino)-2-(benzyloxy)-3-phenylpropanoate→(2R,3Z)-3-(benzylimino)-2-(benzyloxy)propan-1-ol→(2R,3R)-3-(benzylamino)-2-(benzyloxy)-3-phenylpropan-1-ol→(2R,3S)-3-(benzylamino)-2-(benzyloxy)-3-phenylpropan-1-ol→(2R,3S)-3-(benzylamino)-2-(benzyloxy)-3-phenylpropanoic acid→(2R,3S)-3-Phenylisoserine methyl ester→methyl (2R,3S)-3-amino-3-phenyl-2-[(triethylsilyl)oxy]propanoate→(3R,4S)-4-Phenyl-3-[(triethylsilyl)oxy]azetidin-2-one→(3R,4S)-1-Benzoyl-4-phenyl-3-(triethylsiloxy)azetidin-2-one
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