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CAS 403-43-0

4-fluorobenzoyl chloride

Codes: FEZO-005

Application context (from source-drug indications)

Vasomotor symptomsFezolinetantHot flushesFezolinetantMenopausal symptomsFezolinetantProstate cancerFezolinetantBreast cancerFezolinetantRenal impairmentFezolinetant

Source drugs (routes using this intermediate)

DrugTierExpiry
FezolinetantTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

FezolinetantOriginator routesteps: 3total yield: 0.795 g
(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one→(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine→3-methyl-1,2,4-thiadiazole-5-carbohydrazide→(R)-3-methyl-5-(8-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-1,2,4-thiadiazole→4-fluorobenzoyl chloride

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

SupplierProductPrice bandMOQLead timeQualificationsAction
Unibest Nantong cGMP Site3-Methyl-1,2,4-thiadiazole-5-carbohydrazide
Pharmaceutical Intermediates
On requestOn requestOn request
—
Unibest Taizhou GMP-like Site(R)-3-Methylpiperazin-2-one
Pharmaceutical Intermediates
On requestOn requestOn request
—
Qualified Partner — East China API Works(R)-4-(2,4-diMethoxybenzyl)-3-Methylpiperazin-2-one
Pharmaceutical Intermediates
On requestOn requestOn request
—
Unibest Nantong cGMP Site3-Methyl-piperazin-2-one
Pharmaceutical Intermediates
On requestOn requestOn request
—
Unibest Taizhou GMP-like Site5-bromo-3-methyl-1,2,4-thiadiazole
Pharmaceutical Intermediates
On requestOn requestOn request
—
Qualified Partner — East China API Works3-Methyl-[1,2,4]thiadiazole-5-carboxylic acid ethyl ester
Pharmaceutical Intermediates
On requestOn requestOn request
—

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.