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CAS 441741-66-8
methyl (E)-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylate hydrochloride
Codes：PANO-008
Application context (from source-drug indications)
多发性骨髓瘤乳酸帕比司他胶质瘤乳酸帕比司他弥漫性内源性庞汀胶质瘤乳酸帕比司他弥漫性中线胶质瘤乳酸帕比司他骨髓增生异常综合征乳酸帕比司他急性髓细胞样白血病乳酸帕比司他
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 乳酸帕比司他Panobinostat Lactate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(2-methyl-1H-indol-3-yl)ethan-1-amine→methyl (E)-3-(4-formylphenyl)acrylate→4-bromobenzaldehyde→methyl acrylate→methyl (E)-3-(4-(((2-(2-methyl-1H-indol-3-yl)ethyl)amino)methyl)phenyl)acrylate hydrochloride→2-hydroxypropanoic acid→phenylhydrazine→5-chloropentan-2-one
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