← Back to patent-cliff list
CAS 455-14-1
4-(trifluoromethyl)aniline
Codes: LEFU-002
Application context (from source-drug indications)
Rheumatoid arthritisLeflunomide狼疮肾炎LeflunomidePsoriatic arthritisLeflunomideMyelodysplastic syndromeLeflunomideLymphomaLeflunomideSolid tumourLeflunomide
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Leflunomide | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
5-methylisoxazole-4-carbonyl chloride→4-(trifluoromethyl)aniline
5-methylisoxazole-4-carbonyl chloride→4-(trifluoromethyl)aniline
4-(trifluoromethyl)aniline→(ethyl carbonic) 5-methylisoxazole-4-carboxylic anhydride
4-(trifluoromethyl)aniline→(benzyl carbonic) 5-methylisoxazole-4-carboxylic anhydride
4-(trifluoromethyl)aniline→2,4-dichlorophenyl 5-methylisoxazole-4-carboxylate
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.