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CAS 4654-72-2
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(3-((E)-amino(methylthio)methylene)ureido)tetrahydrofuran-3,4-diyl diacetate
Codes: AZAC-003
Application context (from source-drug indications)
幼年型粒单核细胞白血病AzacitidineAcute myeloid leukaemiaAzacitidineMyelodysplastic syndromeAzacitidineChronic myeloid leukaemiaAzacitidineChronic myelomonocytic leukaemiaAzacitidine脑性瘫痪Azacitidine
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Azacitidine | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(2R,3R,4R,5R)-2-(acetoxymethyl)-5-isocyanatotetrahydrofuran-3,4-diyl diacetate→methyl carbamimidothioate→(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(3-((E)-amino(methylthio)methylene)ureido)tetrahydrofuran-3,4-diyl diacetate→(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(4-(methylthio)-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate
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