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CAS 52805-46-6
3-hydroxy-4-methoxybenzonitrile
Codes: GEFT-002
Application context (from source-drug indications)
Non-small cell lung cancerGefitinibLung cancerGefitinibHead and neck cancerGefitinibBreast cancerGefitinib唇肿瘤Gefitinib喉肿瘤Gefitinib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Gefitinib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-hydroxy-4-methoxybenzaldehyde→3-hydroxy-4-methoxybenzonitrile→4-(3-chloropropyl)morpholine→4-methoxy-3-(3-morpholinopropoxy)benzonitrile→4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile→2-amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile→2-amino-4-methoxy-5-(3-morpholinopropoxy)benzamide→7-methoxy-6-(3-morpholinopropoxy)quinazolin-4(1H)-one→4-(3-((4-chloro-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine→3-chloro-4-fluoroaniline
3-hydroxy-4-methoxybenzaldehyde→3-hydroxy-4-methoxybenzonitrile→4-(3-chloropropyl)morpholine→4-methoxy-3-(3-morpholinopropoxy)benzonitrile→4-methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile→2-amino-4-methoxy-5-(3-morpholinopropoxy)benzonitrile→3-chloro-4-fluoroaniline→(E)-N,N'-bis(3-chloro-4-fluorophenyl)formimidamide
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