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CAS 528854-24-2
(aS)-4-tert-Butyl-4,5-dihydro-3H-4lambda5-dinaphtho[2,1-c:1',2'-e]phosphepine-4-thione
Codes：(XVII)101438-70-b
Application context (from source-drug indications)
乳腺癌Paclitaxel/Encequidar mesylate腺癌Paclitaxel/Encequidar mesylate血管肉瘤Paclitaxel/Encequidar mesylate实体瘤Paclitaxel/Encequidar mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Paclitaxel/Encequidar mesylatePaclitaxel/Encequidar mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(aS)-(-)-1,1'-Bi-2-naphthol→(aS)-[1,1'-Binaphthalene]-2,2'-diyl bis(trifluoromethanesulfonate)→Methylmagnesium bromide→(aS)-2,2'-Dimethyl-1,1'-binaphthalene→(aS)-4-tert-Butyl-4,5-dihydro-3H-4lambda5-dinaphtho[2,1-c:1',2'-e]phosphepine-4-thione→(aS)-(4R,4'R)-4,4'-Di-tert-butyl-4,4',5,5'-tetrahydro-3H,3'H-[3,3'-bi-4lambda5-dinaphtho[2,1-c:1',2'-e]phosphepine]-4,4'-dithione
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