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CAS 5337-09-7
methyl 2-bromo-3-nitrobenzoate
Codes：CAND-014
Application context (from source-drug indications)
高血压苯磺酸氨氯地平/坎地沙坦酯
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 苯磺酸氨氯地平/坎地沙坦酯Amlodipine Besylate/Candesartan Cilexetil | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
methyl 2-amino-3-nitrobenzoate→methyl 2-bromo-3-nitrobenzoate→methyl 3-amino-2-bromobenzoate→methyl 2-bromo-3-((diethoxymethylene)amino)benzoate→(2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methanamine→(E)-methyl 2-bromo-3-((ethoxy(((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)amino)methylene)amino)benzoate→1-chloroethyl cyclohexyl carbonate→(E)-1-(((cyclohexyloxy)carbonyl)oxy)ethyl 2-bromo-3-((ethoxy(((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)amino)methylene)amino)benzoate→1-(((cyclohexyloxy)carbonyl)oxy)ethyl 2-ethoxy-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate
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