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CAS 53608-94-9
2,2-diethoxyethanethiol
Codes:LAMI-003
Application context (from source-drug indications)
HIV感染多替拉韦/拉米夫定/艾酚福韦HIV感染拉米夫定/富马酸替诺福韦二吡呋酯慢性乙型肝炎拉米夫定/富马酸替诺福韦二吡呋酯HIV感染依非韦伦/拉米夫定/富马酸替诺福韦二吡呋酯
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 多替拉韦/拉米夫定/艾酚福韦Dolutegravir/Lamivudine/Tenofovir Alafenamide | Tier C — Watch / trade | - |
| 拉米夫定/富马酸替诺福韦二吡呋酯Lamivudine/Tenofovir Disoproxil Fumarate | Tier C — Watch / trade | - |
| 依非韦伦/拉米夫定/富马酸替诺福韦二吡呋酯Efavirenz/Lamivudine/Tenofovir Disoproxil Fumarate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2,3-dihydroxypropyl benzoate→2-oxoethyl benzoate→2,2-diethoxyethanethiol→(5-ethoxy-1,3-oxathiolan-2-yl)methyl benzoate→4-aminopyrimidin-2(1H)-one→((2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl benzoate→benzothioic O-acid→2-bromo-1,1-diethoxyethane→S-(2,2-diethoxyethyl) benzothioate
2,3-dihydroxypropyl benzoate→2-oxoethyl benzoate→2,2-diethoxyethanethiol→(5-ethoxy-1,3-oxathiolan-2-yl)methyl benzoate→4-aminopyrimidin-2(1H)-one→((2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl benzoate→benzothioic O-acid→2-bromo-1,1-diethoxyethane→S-(2,2-diethoxyethyl) benzothioate
2,3-dihydroxypropyl benzoate→2-oxoethyl benzoate→2,2-diethoxyethanethiol→(5-ethoxy-1,3-oxathiolan-2-yl)methyl benzoate→4-aminopyrimidin-2(1H)-one→((2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-oxathiolan-2-yl)methyl benzoate→benzothioic O-acid→2-bromo-1,1-diethoxyethane→S-(2,2-diethoxyethyl) benzothioate
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