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CAS 56-45-1

(S)-2-Amino-3-hydroxypropanoic acid

Codes(I)638294-12-a

Application context (from source-drug indications)

收缩性心力衰竭非奈利酮舒张期心力衰竭非奈利酮心脏衰竭非奈利酮慢性肾功能不全非奈利酮糖尿病肾病非奈利酮二型糖尿病非奈利酮

Source drugs (routes using this intermediate)

DrugTierExpiry
非奈利酮FinerenoneTier C — Watch / trade2030

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

非奈利酮优化路线steps: 8total yield: /
(S)-2-Amino-3-hydroxypropanoic acid(S)-Ethyl 2-amino-3-hydroxypropanoate hydrochloride(S)-Ethyl 2-((tert-butoxycarbonyl)amino)-3-hydroxypropanoate2,2-Dimethyl-6-methyl-1,3-dioxin-4-one(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl 3-oxobutanoate2-Methoxy-4-cyanobenzaldehyde(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl-2-[(4-cyano-2-methoxyphenyl)methylidene]-3-oxobutanoate4-Amino-5-methylpyridin-2(1H)-one(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl 4-(4-cyano-2-methoxyphenyl)-5-hydroxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylate(Diethoxymethoxy)ethane(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylate(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl 4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,6-naphthyridine-3-carboxylate(2S)-2-[(tert-Butoxycarbonyl)amino]-3-ethoxy-3-oxopropyl (4S)-4-(4-cyano-2-methoxyphenyl)-5-ethoxy-2,8-dimethyl-1,4-dihydro-1,6-naphthyridine-3-carboxylate

Intermediates available on this site

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SupplierProductPrice bandMOQLead timeQualifications
Unibest Taizhou GMP-like SiteL-Serine
Pharmaceutical Intermediates
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