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CAS 566-65-4

(5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one

Codes: GANA-004

Application context (from source-drug indications)

CDKL5缺乏症GanaxoloneSeizureGanaxolone癫痫综合征Ganaxolone婴儿痉挛GanaxoloneEpilepsyGanaxoloneTuberous sclerosisGanaxolone

Source drugs (routes using this intermediate)

DrugTierExpiry
GanaxoloneTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

GanaxoloneOptimised routesteps: 2total yield: 5.1 g
(5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one→1-((3R,5S,8R,9S,10S,13S,14S,17S)-10,13-dimethylhexadecahydrospiro[cyclopenta[a]phenanthrene-3,2'-oxiran]-17-yl)ethan-1-one
GanaxoloneOptimised routesteps: 1total yield: 0.983 kg
(5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one

Intermediates available on this site

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