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CAS 586396-61-4
(2S)-N-tert-Butyl-2-hydroxy-4-phenylbutanamide
Codes：Enalapril-060
Application context (from source-drug indications)
心脏和血管疾病阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利高血压阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利高脂血症阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利心脏病阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利原发性高血压马来酸依那普利/叶酸
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 阿托伐他汀/氢氯噻嗪/阿司匹林/依那普利Atorvastatin/Hydrochlorothiazide/Aspirin/Enalapril | Tier C — Watch / trade | - |
| 马来酸依那普利/叶酸Enalapril Maleate/Folic Acid | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(3E)-2-Oxo-4-phenylbut-3-enoic acid→2-Methylpropan-2-amine→2-Methylpropan-2-amine hydrogen chloride→3(E)-N-(tert-Butyl)-2-oxo-4-phenylbutenamide→(2S,3E)-N-tert-Butyl-2-hydroxy-4-phenylbut-3-enamide→(2S)-N-tert-Butyl-2-hydroxy-4-phenylbutanamide→(2S)-2-Hydroxy-4-phenylbutanoic acid→Ethyl 2(S)-hydroxy-4-phenylbutyrate→Benzaldehyde→2-Oxopropanoic acid→Non-denatured ethanol
(3E)-2-Oxo-4-phenylbut-3-enoic acid→2-Methylpropan-2-amine→2-Methylpropan-2-amine hydrogen chloride→3(E)-N-(tert-Butyl)-2-oxo-4-phenylbutenamide→(2S,3E)-N-tert-Butyl-2-hydroxy-4-phenylbut-3-enamide→(2S)-N-tert-Butyl-2-hydroxy-4-phenylbutanamide→(2S)-2-Hydroxy-4-phenylbutanoic acid→Ethyl 2(S)-hydroxy-4-phenylbutyrate→Benzaldehyde→2-Oxopropanoic acid→Non-denatured ethanol
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