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CAS 599-91-7

propyl 4-methylbenzenesulfonate

Codes: PRAM-017

Application context (from source-drug indications)

Restless legs syndromePramipexole Dihydrochloride HydrateParkinson's diseasePramipexole Dihydrochloride HydrateManiaPramipexole Dihydrochloride Hydrate快感缺乏Pramipexole Dihydrochloride HydrateDepressionPramipexole Dihydrochloride HydrateMajor depressive disorderPramipexole Dihydrochloride Hydrate

Source drugs (routes using this intermediate)

DrugTierExpiry
Pramipexole Dihydrochloride HydrateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Pramipexole Dihydrochloride HydrateOptimised routesteps: 5total yield: 0.25 g
PRAM-008→(R)-N-(6-hydroxy-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)acetamide→(R)-2-acetamido-4,5,6,7-tetrahydrobenzo[d]thiazol-6-yl 4-methylbenzenesulfonate→(S)-N-(6-azido-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)acetamide→(S)-N-(6-amino-4,5,6,7-tetrahydrobenzo[d]thiazol-2-yl)acetamide→propyl 4-methylbenzenesulfonate

Intermediates available on this site

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