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CAS 614-03-9

3-[(1S)-1-Hydroxy-2-(methylamino)ethyl]phenol

Codes:Phenylephrine Hydrochloride-020

Application context (from source-drug indications)

感冒布洛芬/盐酸去氧肾上腺素发热布洛芬/盐酸去氧肾上腺素头痛布洛芬/盐酸去氧肾上腺素

Source drugs (routes using this intermediate)

DrugTierExpiry
布洛芬/盐酸去氧肾上腺素Ibuprofen/Phenylephrine HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

布洛芬/盐酸去氧肾上腺素优化路线steps: 9total yield: 146.9g(Phenylephrine Hydrochloride (API))
3-[(1S)-1-Hydroxy-2-(methylamino)ethyl]phenol→3-[(1S)-1-Hydroxy-2-(methylamino)ethyl]phenyl benzoate→3-[(1S)-2-[Acetyl(methyl)amino]-1-hydroxyethyl]phenyl benzoate→3-(N-Acetyl-N-methylglycyl)phenyl benzoate→1-(3-Hydroxyphenyl)-2-(methylamino)ethanone sulfate→3-[1-Hydroxy-2-(methylamino)ethyl]phenol→3-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol→(1R)-1-(3-Hydroxyphenyl)-2-(methylamino)ethyl acetate sulfate

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