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CAS 627-11-2
2-chloroethyl carbonochloridate
Codes：ERDA-017
Application context (from source-drug indications)
尿路上皮癌厄达替尼泌尿系肿瘤厄达替尼
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 厄达替尼Erdafitinib | Tier C — Watch / trade | 2030 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethanol→2-((3,5-dimethoxyphenyl)(3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl)amino)ethyl methanesulfonate→2-chloroethyl carbonochloridate→2-((3,5-dimethoxyphenyl)amino)ethanol→N-(2-((tert-butyldimethylsilyl)oxy)ethyl)-3,5-dimethoxyaniline→Erdafitinib→7-bromo-2-(1-methyl-1H-pyrazol-4-yl)quinoxaline→3,5-dimethoxyaniline→N-(2-((tert-butyldimethylsilyl)oxy)ethyl)-N-(3,5-dimethoxyphenyl)-3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-amine
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