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CAS 640287-98-5
1-[3-(Aminomethyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid
Codes: Berotralstat-014
Application context (from source-drug indications)
遗传性血管性水肿Berotralstat
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Berotralstat | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-(3-[[(tert-Butoxycarbonyl)amino]methyl]phenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid→3-aminobenzonitrile→4,4,4-trifluoro-1-(furan-2-yl)butane-1,3-dione→3-[5-(Furan-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzonitrile→1-(3-Cyanophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid→1-[3-(Aminomethyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid
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