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CAS 64471-43-8
(S)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid
Codes：GLYC-012
Application context (from source-drug indications)
哮喘布地奈德/富马酸福莫特/格隆溴铵慢性阻塞性肺疾病布地奈德/富马酸福莫特/格隆溴铵慢性阻塞性肺疾病马来酸茚达特罗/格隆溴铵
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 布地奈德/富马酸福莫特/格隆溴铵Budesonide/Formoterol fumarate/Glycopyrronium Bromide | Tier B — Position early | - |
| 马来酸茚达特罗/格隆溴铵Indacaterol Maleate/Glycopyrronium Bromide | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
bromocyclopentane→(S)-2-hydroxy-2-phenylacetic acid→(2S,5S)-2-(tert-butyl)-5-phenyl-1,3-dioxolan-4-one→(2S,5S)-2-(tert-butyl)-5-cyclopentyl-5-phenyl-1,3-dioxolan-4-one→(S)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid→methyl (S)-2-cyclopentyl-2-hydroxy-2-phenylacetate→(R)-1-methylpyrrolidin-3-ol→(R)-1-methylpyrrolidin-3-yl (S)-2-cyclopentyl-2-hydroxy-2-phenylacetate
bromocyclopentane→(S)-2-hydroxy-2-phenylacetic acid→(2S,5S)-2-(tert-butyl)-5-phenyl-1,3-dioxolan-4-one→(2S,5S)-2-(tert-butyl)-5-cyclopentyl-5-phenyl-1,3-dioxolan-4-one→(S)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid→methyl (S)-2-cyclopentyl-2-hydroxy-2-phenylacetate→(R)-1-methylpyrrolidin-3-ol→(R)-1-methylpyrrolidin-3-yl (S)-2-cyclopentyl-2-hydroxy-2-phenylacetate
Intermediates available on this site
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