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CAS 646519-93-9
2-(4-((2,4-dioxothiazolidin-5-yl)methyl)phenoxy)-1-(5-ethylpyridin-2-yl)ethyl 4-methylbenzenesulfonate
Codes：PIOG-028
Application context (from source-drug indications)
二型糖尿病苯甲酸阿格列汀/盐酸吡格列酮
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 苯甲酸阿格列汀/盐酸吡格列酮Alogliptin Benzoate/Pioglitazone Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(5-ethylpyridin-2-yl)ethan-1-ol→thiazolidine-2,4-dione→4-hydroxybenzaldehyde→4-(2-(5-ethylpyridin-2-yl)-2-hydroxyethoxy)benzaldehyde→5-ethyl-2-(2-hydroxyethyl)pyridine 1-oxide→1-(5-ethylpyridin-2-yl)ethane-1,2-diyl diacetate→1-(5-ethylpyridin-2-yl)ethane-1,2-diol→4-(5-ethylpyridin-2-yl)-1,3,2-dioxathiolane 2-oxide→1-(5-ethylpyridin-2-yl)-2-(4-formylphenoxy)ethyl 4-methylbenzenesulfonate→(Z)-2-(4-((2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)-1-(5-ethylpyridin-2-yl)ethyl 4-methylbenzenesulfonate→2-(4-((2,4-dioxothiazolidin-5-yl)methyl)phenoxy)-1-(5-ethylpyridin-2-yl)ethyl 4-methylbenzenesulfonate
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