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CAS 69399-79-7

3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl chloride

Codes: (VII)70425-1-a, (III)70425-3-a

Application context (from source-drug indications)

Bacterial infectionFloxacillin sodium蜂窝织炎Floxacillin sodiumChronic renal impairmentFloxacillin sodium

Source drugs (routes using this intermediate)

DrugTierExpiry
Floxacillin sodiumTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Floxacillin sodiumOptimised routesteps: 3total yield: /
(+)-6-Aminopenicillanic acid→Sodium (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate→Potassium (2S,5R,6R)-6-amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate→3-(2-chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl chloride→(2S,5R,6R)-6-([[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl]amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

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