← Back to patent-cliff list
CAS 72447-81-5
1,1-Dimethoxy-3-nitropropane
Codes: (XVIIIa)965082-1-c
Application context (from source-drug indications)
Marginal zone B-cell lymphomaOrelabrutinibMantle cell lymphomaOrelabrutinibChronic lymphocytic leukaemiaOrelabrutinibImmune thrombocytopenic purpuraOrelabrutinibSystemic lupus erythematosusOrelabrutinibMultiple sclerosisOrelabrutinib
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Orelabrutinib | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(4-Phenoxyphenyl)-6-(piperidin-4-yl)pyridine-3-carboxamide→3-Nitropropanal→3-Oxo-3-(4-phenoxyphenyl)propanamide→1-Benzylpiperidin-4-one→1-[(4-Methoxyphenyl)methyl]piperidin-4-one→Acrylaldehyde→1,1-Dimethoxy-3-nitropropane→1,1-Diethoxy-3-nitropropane→1-Benzyl-4-(3,3-dimethoxy-1-nitropropyl)piperidin-4-ol→1-Benzyl-4-(3,3-diethoxy-1-nitropropyl)piperidin-4-ol→4-(3,3-Diethoxy-1-nitropropyl)-1-[(4-methoxyphenyl)methyl]piperidin-4-ol→(2Z)-5-(1-Benzyl-4-hydroxypiperidin-4-yl)-5-nitro-2-(4-phenoxybenzoyl)pent-2-enamide→(2Z)-5-[4-Hydroxy-1-[(4-methoxyphenyl)methyl]piperidin-4-yl]-5-nitro-2-(4-phenoxybenzoyl)pent-2-enamide
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.