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CAS 7326-19-4

(R)-2-hydroxy-3-phenylpropanoic acid

Codes: MITI-022

Application context (from source-drug indications)

Type 2 diabetesMitiglinideDiabetesMitiglinide

Source drugs (routes using this intermediate)

DrugTierExpiry
MitiglinideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

MitiglinideOptimised routesteps: 5total yield: 296 g
(E)-2-amino-3-phenylacrylic acid→(R)-2-hydroxy-3-phenylpropanoic acid→(R)-3-phenyl-2-(tosyloxy)propanoic acid→MITI-024→2-chloro-1-((3aR,7aS)-octahydro-2H-isoindol-2-yl)ethan-1-one→MITI-026

Intermediates available on this site

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