Unibest
← Back to patent-cliff list

CAS 73731-37-0

N-alpha-Fmoc-L-threonine<-fgf->N-(9H-Fluoren-9-ylmethoxycarbonyl)-L-threonine

Codes: Atosiban-160

Application context (from source-drug indications)

产科分娩(早产)Atosiban acetate早产(孕37周前)Atosiban acetateEndometriosisAtosiban acetate

Source drugs (routes using this intermediate)

DrugTierExpiry
Atosiban acetateTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Atosiban acetateOptimised routesteps: 7total yield: /
Resin bound 9H-fluoren-9-ylmethyl (2-amino-2-oxoethyl)carbamate→Resin bound Gly-NH→N5-[1-(4,4-Dimethyl-2,6-dioxocyclohexylidene)ethyl]-N2-[[(9H-fluoren-9-yl)methoxy]carbonyl]-L-ornithine→Resin bound S-(triphenylmethyl)-L-cysteinyl-L-prolyl-N5-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-L-ornithylglycinamide→Resin bound Orn(Dde)-Gly-NH→Resin bound L-prolyl-N5-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)ethyl]-L-ornithylglycinamide→Resin bound Asn-Cys(Trt)-Pro-Orn(Dde)-Gly-NH→N-alpha-Fmoc-L-threonine<-fgf->N-(9H-Fluoren-9-ylmethoxycarbonyl)-L-threonine→Resin bound Thr-Asn-Cys(Trt)-Pro-Orn(Dde)-Gly→N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-asparagine→N-(9-Fluorenylmethoxycarbonyl)-L-proline→N-(9-Fluorenylmethoxycarbonyl)-S-trityl-L-cysteine→N-(9H-Fluoren-9-ylmethoxycarbonyl)glycine

Intermediates available on this site

No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.