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CAS 754157-48-7
(1R,4S)-7-bromo-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
Codes：Sertraline Hydrochloride-008
Application context (from source-drug indications)
强迫性障碍枸橼酸舍曲林
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 枸橼酸舍曲林Sertraline Citrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
7-bromo-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine→(1R)-7-Bromo-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine→N-[(1R)-7-Bromo-1,2,3,4-tetrahydronaphthalen-1-yl]-N-methylformamide→N-[(1R)-7-Bromo-4-oxo-1,2,3,4-tetrahydronaphthalen-1-yl]-N-methylformamide→3,4-Dichlorophenylmagnesium bromide→N-[(1R,4S)-7-bromo-4-(3,4-dichlorophenyl)-4-hydroxy-1,2,3,4-tetrahydronaphthalen-1-yl]-N-methylformamide→N-[(1R,4S)-7-bromo-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]-N-methylformamide→(1R,4S)-7-bromo-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine→(1E,4S)-7-bromo-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-imine→(1S,4S)-7-bromo-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
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