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CAS 762273-01-8
(S)-1-(3-bromophenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol
Codes: MONT-033
Application context (from source-drug indications)
Allergic rhinitisMontelukastAsthmaMontelukastHypersensitivity reactionMontelukastSeasonal allergic rhinitisMontelukastPerennial allergic rhinitisMontelukastExercise-induced asthmaMontelukast
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Montelukast | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetic acid→3-bromobenzaldehyde→1-(3-bromophenyl)prop-2-en-1-ol→methyl 2-iodobenzoate→methyl 2-(3-(3-bromophenyl)-3-oxopropyl)benzoate→methyl (S)-2-(3-(3-bromophenyl)-3-hydroxypropyl)benzoate→(S)-1-(3-bromophenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propan-1-ol→2-(1-(mercaptomethyl)cyclopropyl)acetonitrile→(R)-2-(1-(((1-(3-bromophenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetonitrile→7-chloro-2-vinylquinoline→(R,E)-2-(1-(((1-(3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)acetonitrile→7-chloroquinoline-2-carbaldehyde
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