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CAS 766536-90-7

(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-oxo-4-((trimethylsilyl)amino)-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate

Codes: AZAC-008

Application context (from source-drug indications)

幼年型粒单核细胞白血病AzacitidineAcute myeloid leukaemiaAzacitidineMyelodysplastic syndromeAzacitidineChronic myeloid leukaemiaAzacitidineChronic myelomonocytic leukaemiaAzacitidine脑性瘫痪Azacitidine

Source drugs (routes using this intermediate)

DrugTierExpiry
AzacitidineTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

AzacitidineProcess routesteps: 3total yield: 1.504 kg
4-amino-1,3,5-triazin-2(1H)-one→N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine→(2S,3R,4R,5R)-5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate→(2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-oxo-4-((trimethylsilyl)amino)-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate

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