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CAS 774244-52-9
(4R)-4-[[tert-Butyl(dimethyl)silyl]oxy]-3,4-dihydronaphthalen-1(2H)-one
Codes：Sertraline Hydrochloride-042
Application context (from source-drug indications)
强迫性障碍枸橼酸舍曲林
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| 枸橼酸舍曲林Sertraline Citrate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(1R)-4-(3,4-Dichlorophenyl)-1,2-dihydronaphthalen-1-ol→2,3-Dihydronaphthalene-1,4-dione→(4R)-4-Hydroxy-3,4-dihydronaphthalen-1(2H)-one→(4R)-4-[[tert-Butyl(dimethyl)silyl]oxy]-3,4-dihydronaphthalen-1(2H)-one→3,4-Dichlorophenylmagnesium bromide→4-bromo-1,2-dichlorobenzene→Sertraline Hydrochloride-044
Intermediates available on this site
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